Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0003p020 | (1) | SRF2016

Effects of the chemotherapy drugs cisplatin and doxorubicin on the follicles of the human ovary

Liu Jin , Lopes Federica , Morgan Stephanie , Nevin Lucy , Telfer Evelyn , Anderson Richard A , Spears Norah

Introduction: The effect of chemotherapy treatment on premenopausal women’s fertility has long been of concern. Here, we investigate the direct actions of chemotherapy drugs on the human ovary, examining effects of two commonly used drugs, cisplatin and doxorubicin.Method: Ovarian cortical tissue samples were collected from patients aged 27–34 who were undergoing elective caesarean section, with informed consent and Ethical Committee approval. ...